Threshold estimation based on a p-value framework in dose-response and regression settings
نویسندگان
چکیده
منابع مشابه
Threshold estimation based on a p-value framework in dose-response and regression settings.
We use p-values to identify the threshold level at which a regression function leaves its baseline value, a problem motivated by applications in toxicological and pharmacological dose-response studies and environmental statistics. We study the problem in two sampling settings: one where multiple responses can be obtained at a number of different covariate levels, and the other the standard regr...
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We investigate the large sample behavior of a p-value based procedure for estimating the threshold level at which a regression function takes off from its baseline value – a problem that frequently arises in environmental statistics, engineering and other related fields. The estimate is constructed via fitting a “stump” function to approximate p-values obtained from tests for deviation of the r...
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We investigate the large sample behavior of a p-value based procedure for estimating the threshold level at which a regression function takes off from its baseline value, a problem arising in dose-response studies, engineering and other related fields. We study the procedure under the so called “dose-response” setting, where several responses can be obtained at each covariate-level. The estimat...
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We use p–values as a discrepancy criterion for identifying the threshold value at which a regression function takes off from its baseline value – a problem that is motivated by applications in omics experiments, systems engineering, pharmacological dose-response studies and astronomy. In this paper, we study the problem in a controlled sampling setting, where multiple responses, discrete or con...
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ژورنال
عنوان ژورنال: Biometrika
سال: 2011
ISSN: 0006-3444,1464-3510
DOI: 10.1093/biomet/asr051